It may depend on your age, health conditions and other medications you may be currently taking.
The same medicinal ingredients (acetaminophen, ibuprofen, naproxen sodium, acetylsalicylic acid) are found in hundreds of commonly used oral over-the-counter and prescription medicines. And if you take more than one medicine with the same kind of medicinal ingredient at a time, it can increase your chances of harmful side effects. Nobody can remember what’s in hundreds of medicines. Check every label and take ONLY 1 medicine that contains the same kind of medicinal ingredient at a time.
What the warnings, directions, and other label facts tell you.
Directions for acetaminophen and NSAIDs—all in one place.
Directions by weight and age for acetaminophen and ibuprofen.